Carey F. Li, Ian R. Henderson, Liang Song, Nina Fedoroff, Thierry Lagrange, Steven E. Jacobsen. Dynamic Regulation of ARGONAUTE4 within Multiple Nuclear Bodies in Arabidopsis thaliana. PLoS Genetics 2008; 4(2): article e27.

Yana V. Bernatavichute, Xiaoyu Zhang, Shawn Cokus, Matteo Pellegrini & Steven E. Jacobsen Genome-wide association of histone H3 lysine nine methylation with CHG DNA methylation in Arabidopsis thaliana. PLoS ONE 2008; 3, e3156: .

Edward Kraft, Magnolia Bostick, Steven E. Jacobsen & Judy Callis ORTH/VIM proteins that regulate DNA methylation are functional ubiquitin E3 ligases. Plant Journal 2008; DOI: 10.1111/j.1365-313X.2008.03631.x: .

Juliana J. Oh, Baher N. Boctor, Cynthia A. Jimenez, Roberto Lopez, Ashley K. Koegel, Eileen O. Taschereau, Diana T. Phan, Steven E. Jacobsen, Dennis J. Slamon Promoter methylation study of the H37/RBM5 tumor suppressor gene from the 3p21.3 human lung cancer tumor suppressor locus. Human Genetics 2008; 123: 55-64.

Lianna M. Johnson, Julie A. Law, Anuj Khattar, Ian R. Henderson, Steven E. Jacobsen SRA-Domain Proteins Required for DRM2-Mediated De Novo DNA Methylation. PLoS Genetics 2008; 4(11): e1000280.

Ian R. Henderson & Steven E. Jacobsen Sequencing sliced ends reveals microRNA targets. Nature Biotechnology 2008; 26: 881-882.

Shawn J. Cokus, Suhua Feng, Xiaoyu Zhang, Zugen Chen, Barry Merriman, Christian D. Haudenschild, Sriharsa Pradhan, Stanley F. Nelson, Matteo Pellegrini & Steven E. Jacobsen Shotgun bisulphite sequencing of the Arabidopsis genome reveals DNA methylation patterning. Nature 2008; 452: 215-219.

Ian R. Henderson & Steven E. Jacobsen Tandem repeats upstream of the Arabidopsis endogene SDC recruit non-CG DNA methylation and initiate siRNA spreading. Genes and Development 2008; 22: 1597?1606.

Alan M. Jones, Joanne Chory, Jeffery L. Dangl, Mark Estelle, Steven E. Jacobsen, Elliot M. Meyerowitz, Magnus Nordborg & Detlef Weigel The Impact of Arabidopsis on Human Health: Diversifying Our Portfolio. Cell 2008; 133: 939-943.

Hideharu Hashimoto, John R. Horton, Xing Zhang, Magnolia Bostick, Steven E. Jacobsen & Xiaodong Cheng The SRA domain of UHRF1 flips 5-methylcytosine out of the DNA helix. Nature 2008; 455: 826-829.

Ian R. Henderson and Steven E. Jacobsen Epigenetic inheritance in plants. Nature 2007; 447: 418-424.

Mahmoud El-Shami, Dominique Pontier, Sylvie Lahmy, Laurence Braun, Claire Picart, Danielle Vega, Mohamed-Ali Hakimi, Steven E. Jacobsen, Richard Cooke and Thierry Lagrange Reiterated WG/GW motifs form functionally and evolutionarily conserved ARGONAUTE-binding platforms in RNAi-related components. Genes & Development 2007; 21: 2539-2544.

Xiaoyu Zhang, Ian R. Henderson, Cheng Lu, Pamela J. Green, and Steven E. Jacobsen Role of RNA polymerase IV in plant small RNA metabolism. Proceedings of the National Academy of Sciences. 2007; 104: 4536-4541.

Xiaoyu Zhang, Sophie Germann, Bartlomiej J Blus, Sepideh Khorasanizadeh, Valerie Gaudin & Steven E Jacobsen The Arabidopsis LHP1 protein colocalizes with histone H3 Lys27 trimethylation. Nature Structural & Molecular Biology. 2007; 14(9): 869-71.

Lianna M. Johnson, Magnolia Bostick, Xiaoyu Zhang, Edward Kraft, Ian Henderson, Judy Callis and Steven E. Jacobsen The SRA methyl-cytosine-binding domain links DNA and histone methylation.. Current Biology 2007; 17(4): 379-384.

Magnolia Bostick, Jong Kyong Kim, Pierre-Olivier Esteve, Amander Clark, Sriharsa Pradhan, Steven E. Jacobsen UHRF1 plays a role in maintaining DNA methylation in mammalian cells. Science. 2007; 317: 1760-1764.

Xiaoyu Zhang, Oliver Clarenz, Shawn Cokus, Yana V. Bernatavichute, Matteo Pellegrini, Justin Goodrich and Steven E. Jacobsen Whole-Genome Analysis of Histone H3 Lysine 27 Trimethylation in Arabidopsis. PLoS Biology. 2007; 5(5): 1026-1035 (article e129).

Li CF, Pontes O, El-Shami M, Henderson IR, Bernatavichute YV, Chan SWL, Lagrange T, Pikaard CS and Jacobsen SE An ARGONAUTE4-containing nuclear processing center colocalized with Cajal bodies in Arabidopsis thaliana. Cell. 2006; 126: 93-106.

Chin HG, Patnaik D, Estve PO, Jacobsen SE, Pradhan S Catalytic properties and kinetic mechanism of human recombinant Lys-9 histone H3 methyltransferase SUV39H1: participation of the chromodomain in enzymatic catalysis. Biochemistry. 2006; 10: 3272-3284.

Henderson IR, Zhang X, Lu C, Johnson L, Meyers BC, Green PL and Jacobsen SE Dissecting Arabidopsis thaliana DICER function in small RNA processing, gene silencing and DNA methylation patterning. Nature Genetics. 2006; 38: 721-725.

Sung S, He Y, Eshoo TW, Tamada Y, Johnson L, Nakahigashi K, Goto K, Jacobsen SE and Amasino RM Epigenetic maintenance of the vernalized state in Arabidopsis thaliana requires LIKE HETEROCHROMATIN PROTEIN 1. Nature Genetics. 2006; 38: 706-710.

Xiaoyu Zhang and Steven E. Jacobsen. Genetic Analysis of DNA methyltransferases in Arabidopsis.. Cold Spring Harbor Symposia on Quantitative Biology. 2006; 71: 439-447.

Xiaoyu Zhang, Junshi Yazaki, Ambika Sundaresan, Shawn Cokus, Simon W. L. Chan, Huaming Chen, Ian R. Henderson, Paul Shinn, Matteo Pellegrini, Steve E. Jacobsen and Joseph R. Ecker Genome-wide High-Resolution Mapping and Functional Analysis of DNA Methylation in Arabidopsis. Cell. 2006; 126(6): 1189-1201.

Peng Peng, Simon W. L. Chan, Govind Shah, Steve E. Jacobsen Increased outcrossing in hothead mutants. Nature 2006; 443(doi: 10.1038/nature05251): .

Mylne JS, Barrett L, Tessadori F, Mesnage S, Johnson L, Bernatavichute YV, Jacobsen SE, Fransz P and Dean C LHP1, the Arabidopsis homologue of HETEROCHROMATIN PROTEIN1, is required for epigenetic silencing of FLC. Proc. Nat. Acad. Sci. U. S. A.. 2006; 103: 5012-5017.

Goll MG, Kirpekar F, Maggert KA, Yoder JA, Hsieh CL, Zhang X, Golic KG, Jacobsen SE, Bestor TH Methylation of tRNA-Asp by the DNA Methyltransferase Homolog Dnmt2. Science. 2006; 311: 395-398.

Cheng Lu, Karthik Kulkarni, Fr??d??ric F. Souret, Ramesh MuthuValliappan, Shivakundan Singh Tej, R. Scott Poethig, Ian R. Henderson, Steven E. Jacobsen, Wenzhong Wang, Pamela J. Green, and Blake C. Meyers MicroRNAs and other small RNAs enriched in the Arabidopsis RNA-dependent RNA polymerase-2 mutant. Genome Research. 2006; 16: 1276-1288.

Chan SWL, Henderson IR, Zhang X, Shah G, Chien JSC and Jacobsen SE RNAi, DRD1, and histone methylation actively target developmentally important non-CG DNA methylation in Arabidopsis. PLoS Genetics. 2006; 2(6): 791-797 (article e83).

Pontes O, Li CF, Nunes PC, Haag J, Ream T, Vitins A, Jacobsen SE and Pikkard CS The Arabidopsis chromatin-modifying nuclear siRNA pathway involves a nucleolar RNA processing center. Cell. 2006; 126: 79-92.

Simon W. L. Chan, Xiaoyu Zhang, Yana V. Bernatavichute, Steve E. Jacobsen Two-step recruitment of RNA-directed DNA methylation to tandem repeats. PLoS Biology. 2006; 4(11): 1923-1933 (article e363).

Tran RK, Zilberman D, de Busto C, Ditt RF, Henikoff JG, Lindroth AM, Delrow J, Boyle T, Kwong S, Bryson TD, Jacobsen SE and Henikoff S Chromatin and siRNA pathways cooperate to maintain DNA methylation of small transposable elements in Arabidopsis. Genome Biology. 2005; 6(R90): .

Johnson L, Mollah S, Garcia BA, Muratore TL, Shabanowitz J, Hunt DF, Jacobsen SE Mass spectrometry analysis of Arabidopsis histone H3 reveals distinct combinations of post-translational modifications.. Nucleic acids research. . 2004; 32(22): 6511-8.

Jackson JP, Lindroth AM, Cao X, Jacobsen SE Control of CpNpG DNA methylation by the KRYPTONITE histone H3 methyltransferase. Nature. 2002; 416(6880): 556-560.

Cao X, Jacobsen SE Role of the Arabidopsis DRM methyltransferases in de novo DNA methylation and gene silencing. Current Biology. 2002; 12(13): 1138-1144.

Eckardt NAA, Araki T, Benning C, Cubas P, Goodrich J, Jacobsen SE, Masson P, Nambara E, Simon R, Somerville S and Wasteneys G Arabidopsis Research 2001. Plant Cell. 2001; 13: 1973-1982.

Cao X, Springer NM, Muszynski MG, Phillips RL, Kaeppler S, Jacobsen SE Conserved plant genes with similarity to mammalian de novo DNA methyltransferases. PNAS. 2000; 97(9): 4979-4984.

Soppe WJJ, Jacobsen SE, Alonso-Blanco C, Jackson J, Kakutani T,Koornneef M and Peeters AJM The late flowering phenotype of fwa mutants is caused by gain of function epi-alleles at a homeodomain gene. Molecular Cell. 2000; 6(4): 791-802.

Jacobsen SE, Running MP and Meyerowitz EM Disruption of an RNA helicase/ RNAse III homologue in Arabidopsis causes unregulated cell division in floral meristems. Development. 1999; 126(23): 5231-5243.

Jacobsen SE, Olszewski NE, Meyerowitz EM SPINDLY's role in the gibberellin response pathway.. Symposia of the Society for Experimental Biology. . 1997; 51: 73-8.

Jacobsen SE, Olszewski NE Gibberellins regulate the abundance of RNAs with sequence similarity to proteinase inhibitors, dioxygenases and dehydrogenases.. Planta. . 1996; 198(1): 78-86.

Jacobsen SE, Shi L, Xin Z, Olszewski NE Gibberellin-induced changes in the translatable mRNA populations of stamens and shoots of gibberellin-deficient tomato.. Planta. . 1994; 192(3): 372-8.

Jacobsen SE and Olszewski NE Characterization of the arrest in anther development associated with gibberellin deficiency of the gib-1 mutant of tomato. Plant Physiology 1991; 97: 409-414.

Zemach A, Li Y, Wayburn B, Ben-Meir H, Kiss V, Avivi Y, Kalchenko V, Jacobsen SE, Grafi G DDM1 binds Arabidopsis methyl-CpG binding domain proteins and affects their subnuclear localization.. The Plant cell.. 2005; 17(5): 1549-58.

Chan SW, Henderson IR, Jacobsen SE Gardening the genome: DNA methylation in Arabidopsis thaliana.. Nature reviews. Genetics. . 2005; 6(5): 351-60.

Tran RK, Henikoff JG, Zilberman D, Ditt RF, Jacobsen SE, Henikoff S DNA methylation profiling identifies CG methylation clusters in Arabidopsis genes.. Current biology : CB. . 2005; 15(2): 154-9.

Mockler TC, Chan S, Sundaresan A, Chen H, Jacobsen SE, Ecker JR Applications of DNA tiling arrays for whole-genome analysis.. Genomics. . 2005; 85(1): 1-15.

Patnaik D, Chin HG, Esteve PO, Benner J, Jacobsen SE, Pradhan S Substrate specificity and kinetic mechanism of mammalian G9a histone H3 methyltransferase.. The Journal of biological chemistry. . 2004; 279(51): 53248-58.

Lindroth AM, Shultis D, Jasencakova Z, Fuchs J, Johnson L, Schubert D, Patnaik D, Pradhan S, Goodrich J, Schubert I, Jenuwein T, Khorasanizadeh S, Jacobsen SE Dual histone H3 methylation marks at lysines 9 and 27 required for interaction with CHROMOMETHYLASE3.. The EMBO journal. . 2004; 23(21): 4286-96.

Morris KV, Chan SW, Jacobsen SE, Looney DJ Small interfering RNA-induced transcriptional gene silencing in human cells.. Science. . 2004; 305(5688): 1289-92.

Zilberman D, Cao X, Johansen LK, Xie Z, Carrington JC, Jacobsen SE Role of Arabidopsis ARGONAUTE4 in RNA-directed DNA methylation triggered by inverted repeats.. Current biology : CB. . 2004; 14(13): 1214-20.

Xie Z, Johansen LK, Gustafson AM, Kasschau KD, Lellis AD, Zilberman D, Jacobsen SE, Carrington JC Genetic and functional diversification of small RNA pathways in plants.. PLoS biology. . 2004; 2(5): 642-652.

Jackson JP, Johnson L, Jasencakova Z, Zhang X, PerezBurgos L, Singh PB, Cheng X, Schubert I, Jenuwein T, Jacobsen SE Dimethylation of histone H3 lysine 9 is a critical mark for DNA methylation and gene silencing in Arabidopsis thaliana.. Chromosoma. . 2004; 112(6): 308-15.

Chan SW, Zilberman D, Xie Z, Johansen LK, Carrington JC, Jacobsen SE RNA silencing genes control de novo DNA methylation. Science. 2004; 303(5662): 1336.

Kinoshita T, Miura A, Choi Y, Kinoshita Y, Cao X, Jacobsen SE, Fischer RL, Kakutani T One-way control of FWA imprinting in Arabidopsis endosperm by DNA methylation.. Science. . 2004; 303(5657): 521-3.

Cao X, Aufsatz W, Zilberman D, Mette MF, Huang MS, Matzke M, Jacobsen SE Role of the DRM and CMT3 methyltransferases in RNA-directed DNA methylation.. Current biology : CB. . 2003; 13(24): 2212-7.

Kato M, Miura A, Bender J, Jacobsen SE, Kakutani T Role of CG and non-CG methylation in immobilization of transposons in Arabidopsis.. Current biology : CB. . 2003; 13(5): 421-6.

Zilberman D, Cao X, Jacobsen SE ARGONAUTE4 control of locus-specific siRNA accumulation and DNA and histone methylation.. Science. . 2003; 299(5607): 716-9.

Cao X, Jacobsen SE Locus-specific control of asymmetric and CpNpG methylation by the DRM and CMT3 methyltransferase genes.. Proceedings of the National Academy of Sciences of the United States of America. . 2002; 99 Suppl 4(Suppl 4): 16491-8.

Soppe WJ, Jasencakova Z, Houben A, Kakutani T, Meister A, Huang MS, Jacobsen SE, Schubert I, Fransz PF DNA methylation controls histone H3 lysine 9 methylation and heterochromatin assembly in Arabidopsis.. The EMBO journal. . 2002; 21(23): 6549-59.

Schauer SE, Jacobsen SE, Meinke DW, Ray A DICER-LIKE1: blind men and elephants in Arabidopsis development.. Trends in plant science. . 2002; 7(11): 487-91.

Johnson L, Cao X, Jacobsen S Interplay between two epigenetic marks. DNA methylation and histone H3 lysine 9 methylation.. Current biology : CB. . 2002; 12(16): 1360-7.

Choi Y, Gehring M, Johnson L, Hannon M, Harada JJ, Goldberg RB, Jacobsen SE, Fischer RL DEMETER, a DNA glycosylase domain protein, is required for endosperm gene imprinting and seed viability in arabidopsis.. Cell. . 2002; 110(1): 33-42.

Malone CS, Miner MD, Doerr JR, Jackson JP, Jacobsen SE, Wall R, Teitell M CmC(A/T)GG DNA methylation in mature B cell lymphoma gene silencing.. Proceedings of the National Academy of Sciences of the United States of America. . 2001; 98(18): 10404-9.

Lindroth AM, Cao X, Jackson JP, Zilberman D, McCallum CM, Henikoff S, Jacobsen SE Requirement of CHROMOMETHYLASE3 for maintenance of CpXpG methylation.. Science. . 2001; 292(5524): 2077-80.

Kishimoto N, Sakai H, Jackson J, Jacobsen SE, Meyerowitz EM, Dennis ES, Finnegan EJ Site specificity of the Arabidopsis METI DNA methyltransferase demonstrated through hypermethylation of the superman locus.. Plant molecular biology. . 2001; 46(2): 171-83.

Sakai H, Krizek BA, Jacobsen SE, Meyerowitz EM Regulation of SUP expression identifies multiple regulators involved in arabidopsis floral meristem development.. The Plant cell. . 2000; 12(9): 1607-18.

Jacobsen SE, Sakai H, Finnegan EJ, Cao X, Meyerowitz EM Ectopic hypermethylation of flower-specific genes in Arabidopsis.. Current biology : CB. . 2000; 10(4): 179-86.

Jacobsen SE Gene silencing: Maintaining methylation patterns.. Current biology : CB. . 1999; 9(16): R617-9.

Jacobsen SE, Meyerowitz EM Hypermethylated SUPERMAN epigenetic alleles in arabidopsis.. Science. . 1997; 277(5329): 1100-3.

Leon-Kloosterziel KM, Gil MA, Ruijs GJ, Jacobsen SE, Olszewski NE, Schwartz SH, Zeevaart JA, Koornneef M Isolation and characterization of abscisic acid-deficient Arabidopsis mutants at two new loci.. The Plant journal : for cell and molecular biology. . 1996; 10(4): 655-61.

Jacobsen SE, Binkowski KA, Olszewski NE SPINDLY, a tetratricopeptide repeat protein involved in gibberellin signal transduction in Arabidopsis.. Proceedings of the National Academy of Sciences of the United States of America. . 1996; 93(17): 9292-6.

Clark SE, Jacobsen SE, Levin JZ, Meyerowitz EM The CLAVATA and SHOOT MERISTEMLESS loci competitively regulate meristem activity in Arabidopsis.. Development (Cambridge, England) . 1996; 122(5): 1567-75.

Jacobsen SE, Olszewski NE Mutations at the SPINDLY locus of Arabidopsis alter gibberellin signal transduction.. The Plant cell. . 1993; 5(8): 887-96.